On statin therapy


of established CVD
patients do not achieve
LDL-C < 70 mg/dL1,*

Even on high-intensity statins


of established CVD
patients do not achieve
LDL-C < 70 mg/dL2,†

  • Multiple etiologies may exist for failure to achieve desired LDL-C, including nonadherence, very high baseline LDL-C, and hyporesponsiveness to therapy3-5

*2011-2012 NHANES: A data analysis examined 131 established CVD patients taking statin therapy, representing 5.87 million individuals with established CVD in the US. Patients with established CVD were defined as those who reported being told by an HCP they had CHD, angina, MI, or stroke in the past (PAD and TIA were not captured in the survey). Statin use was self-reported and confirmed at the patient’s NHANES visit.1

Data obtained from the Truven Health MarketScan® Research databases claims data. Established CVD was defined according to the ACC/AHA criteria for clinical ASCVD. High-intensity statin was defined as > 30 mg/day atorvastatin, > 15 mg/day rosuvastatin, and > 60 mg/day simvastatin. Patients with a valid LDL-C assessment in 2013 were included if they were continuously enrolled in the dataset for 24 months prior to their LDL-C assessment; 2,707 patients met the established CVD criteria.2

ASCVD = atherosclerotic cardiovascular disease; CVD = cardiovascular disease; HCP = healthcare professional; MI = myocardial infarction; NHANES = National Health and Nutrition Examination Survey; TIA = transient ischemic attack.