Median LDL-C levels in Repatha® Outcomes Study2

Median LDL-C levels in Repatha® Outcomes Study Median LDL-C levels in Repatha® Outcomes Study

Weeks

Calculated LDL-C, mg/dL

63%

Reduction in LDL-C at Week 121,4

Repatha® + Statin Median Achieved LDL-C 26 mg/dL

Placebo + Statin Median Baseline LDL-C 92 mg/dL

  • Almost 90% of patients achieved LDL-C levels less than 70 mg/dL with Repatha® added to a statin3

  • At Week 12, Repatha® added to a statin demonstrated a dramatic 63% reduction in LDL-C (95% CI, 62-63) and 59% at Week 48 (95% CI, 58-60; P < 0.001)1,4

  • 76% of patients taking Repatha® added to a statin had at least one LDL-C value of < 25 mg/dL1

  • The intensive LDL-C reduction achieved with Repatha® was sustained for the duration of the study2

  • Repatha® significantly reduced LDL-C levels without dose titration1

CI = confidence interval; CV = cardiovascular; LDL-C = low-density lipoprotein cholesterol.